Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Tetramethylammonium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.67 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.67 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylammonium Ion SCHEMBL130473 | 1.00 | — | — | |
| Tetramethylammonium Ion SCHEMBL17907279 | 1.00 | CHRNB2 (0.67) | CHRNB2CHRNA7CHRNA4 | |
| Tetramethylammonium Ion SCHEMBL6979652 | 1.00 | — | — | |
| Tetramethylammonium Ion SCHEMBL28419141 | 0.93 | — | — | |
| Tetramethylammonium Ion SCHEMBL28374142 | 0.93 | CHRNB2 (0.57) | CHRNB2CHRNA7CHRNA4 | |
| Tetramethylammonium Ion SCHEMBL11860746 | 0.93 | — | — | |
| Tetramethylammonium Ion SCHEMBL11860742 | 0.93 | — | — | |
| Tetramethylammonium Ion SCHEMBL11854713 | 0.93 | — | — | |
| Tetramethylammonium Ion SCHEMBL9640622 | 0.93 | — | — | |
| Tetramethylammonium Ion SCHEMBL130472 | 0.91 | CHRNB2 (0.80) | CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582399-B1 | Method for the alteration of siliceous materials in Bayer process liquors | NALCO CHEMICAL CO (US) | 1996-01-31 | — | — | EP | disclosed |
| US-5314626-A | Method for the alteration of siliceous materials from Bayer process liquids | NALCO CHEMICAL COMPANY (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0582399-A2 | Method for the alteration of siliceous materials in Bayer process liquors | NALCO CHEMICAL COMPANY (US) | 1994-02-09 | — | — | EP | disclosed |