Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025977 | 0.84 | CHRNA7 (0.41) | CHRNA7 | |
| SCHEMBL9585060 | 0.84 | CHRNA7 (0.41) | CHRNA7 | |
| SCHEMBL2968389 | 0.84 | CHRNA7 (0.41) | CHRNA7 | |
| SCHEMBL9710931 | 0.84 | CHRNA7 (0.41) | CHRNA7 | |
| SCHEMBL9710719 | 0.81 | — | — | |
| SCHEMBL9458898 | 0.81 | — | — | |
| Oxalic Acid SCHEMBL9710958 | 0.80 | CHRNA7 (0.39) | CHRNA7 | |
| SCHEMBL9430775 | 0.77 | CHRNA7 (0.49) | CHRNA7 | |
| SCHEMBL5026862 | 0.77 | CHRNA7 (0.38) | CHRNA7 | |
| SCHEMBL5026858 | 0.77 | CHRNA7 (0.38) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327155-A2 | Pyrazines, pyrimidines and pyridazines, useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-08-09 | — | — | EP | claimed |
| US-5574053-A | Method for treating anxiety | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5574029-A | Method for treating anxiety | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5574028-A | SEDATIVES | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5260293-A | Simulate central muscarinic acetlycholine receptors | MERCK SHARP & DOHME LIMITED (GB) | 1993-11-09 | — | — | US | disclosed |
| EP-0327155-A2 | Pyrazines, pyrimidines and pyridazines, useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-08-09 | — | — | EP | disclosed |