SCHEMBL8961520

SCHEMBL8961520

C=CCOc1ccc(-c2ccc(-c3ccc(C4CCC(C5CCC(CC/C=C/C)CC5)CC4)c(F)c3)cc2)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.33
DGAT1 O75907 1/20 0.31
HTR2C P28335 3/20 0.31
HTR2B P41595 2/20 0.31
OPRL1 P41146 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8961589 0.92 FFAR4 (0.35) FFAR4DGAT1HTR2CHTR2BOPRL1
SCHEMBL8961389 0.91 FFAR4 (0.35) FFAR4DGAT1OPRL1
SCHEMBL8960227 0.90 HTR2C (0.33) FFAR4DGAT1HTR2CHTR2BOPRL1
SCHEMBL8934719 0.89 FFAR4 (0.37) FFAR4DGAT1HTR2CHTR2BOPRL1
SCHEMBL8961506 0.89 FFAR4 (0.34) FFAR4DGAT1OPRL1
SCHEMBL8961480 0.89 DGAT1 (0.35) FFAR4DGAT1OPRL1
SCHEMBL8934545 0.89 FFAR4 (0.36) FFAR4DGAT1OPRL1
SCHEMBL8961539 0.88 FFAR4 (0.33) FFAR4DGAT1
SCHEMBL8961501 0.87 FFAR4 (0.33) FFAR4DGAT1
SCHEMBL8959470 0.87 PDE4A (0.32) HTR2CHTR2BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed
EP-2206695-A1 TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2010-07-14 EP disclosed