Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961409 | 0.93 | LMNA (0.40) | LMNAHTTADRA1DADRA1AADRA1B | |
| SCHEMBL8961474 | 0.90 | LMNA (0.43) | LMNAHTTADRA1DADRA1AADRA1B | |
| SCHEMBL8961554 | 0.83 | LMNA (0.45) | LMNAHTTADRA1DADRA1AADRA1B | |
| Pramiracetam SCHEMBL195465 | 0.78 | LMNA (0.48) | LMNAHTTADRA1DADRA1AADRA1B | |
| Pramiracetam SCHEMBL121209 | 0.77 | LMNA (0.47) | LMNAHTTADRA1DADRA1AADRA1B | |
| Pramiracetam SCHEMBL11556360 | 0.77 | LMNA (0.47) | LMNAHTTADRA1DADRA1AADRA1B | |
| SCHEMBL10580659 | 0.77 | LMNA (0.38) | LMNAHTTADRA1DADRA1AADRA1B | |
| SCHEMBL11553497 | 0.77 | HTT (0.50) | LMNAHTTADRA1DADRA1AADRA1B | |
| Pramiracetam SCHEMBL1171471 | 0.76 | LMNA (0.46) | LMNAHTTADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL11555232 | 0.76 | HTT (0.49) | LMNAHTTADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299495-B1 | 1-Pyrrolidineacetamide derivatives and use thereof | SANWA KAGAKU KENKYUSHO CO (JP) | 1996-02-07 | — | — | EP | claimed |
| US-4939126-A | 1-pyrrolidineacetamide derivatives and use thereof | SANWA KAGAKU KENKYUSHO CO. LTD. (JP) | 1990-07-03 | — | — | US | claimed |
| EP-0299495-B1 | 1-Pyrrolidineacetamide derivatives and use thereof | SANWA KAGAKU KENKYUSHO CO (JP) | 1996-02-07 | — | — | EP | disclosed |
| US-4939126-A | 1-pyrrolidineacetamide derivatives and use thereof | SANWA KAGAKU KENKYUSHO CO. LTD. (JP) | 1990-07-03 | — | — | US | disclosed |