Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 8/20 | 0.82 |
| ▸ | WNT3A | P56704 | 6/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237626 | 0.92 | MEN1 (0.76) | CTNNB1WNT3AMEN1KMT2AALDH1A1 | |
| SCHEMBL29458253 | 0.92 | MEN1 (0.76) | CTNNB1WNT3AMEN1KMT2AALDH1A1 | |
| SCHEMBL15969410 | 0.90 | CTNNB1 (1.00) | CTNNB1WNT3AALDH1A1MAPK1PKM | |
| SCHEMBL10027735 | 0.90 | CTNNB1 (0.82) | CTNNB1WNT3AMEN1KMT2AALDH1A1 | |
| SCHEMBL5381632 | 0.87 | MEN1 (0.69) | CTNNB1WNT3AMEN1KMT2AALDH1A1 | |
| SCHEMBL26475136 | 0.86 | MEN1 (0.64) | CTNNB1WNT3AMEN1KMT2AALDH1A1 | |
| SCHEMBL1660203 | 0.85 | CTNNB1 (0.61) | CTNNB1WNT3AMEN1KMT2AALDH1A1 | |
| SCHEMBL29168373 | 0.84 | CTNNB1 (0.63) | CTNNB1WNT3AMEN1KMT2AALDH1A1 | |
| SCHEMBL3519624 | 0.84 | RAB9A (0.70) | CTNNB1WNT3AMEN1KMT2AALDH1A1 | |
| SCHEMBL1516344 | 0.83 | NPC1 (0.83) | CTNNB1WNT3AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507013-B1 | Process for the preparation of aromatic beta-diketones | WITCO CORP (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0507013-A1 | Process for the preparation of aromatic beta-diketones | WITCO CORPORATION (US) | 1992-10-07 | — | — | EP | disclosed |
| US-5015777-A | Reaction of an acetophenone and an aliphatic ester or an ester of benzoic acid in the presence of sodium alkoxide condensation agent in an aromatic solvent | WITCO CORPORATION (US) | 1991-05-14 | — | — | US | disclosed |