Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333439 | 0.81 | HSD17B10 (0.48) | ALDH1A1HSD17B10TDP1TSHRSMN1; SMN2 | |
| SCHEMBL27780773 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TDP1TSHRSMN1; SMN2 | |
| SCHEMBL57184 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TDP1TSHRSMN1; SMN2 | |
| SCHEMBL29378762 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TDP1TSHRSMN1; SMN2 | |
| SCHEMBL1135592 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TSHRSMN1; SMN2MAPT | |
| SCHEMBL28192836 | 0.78 | ALDH1A1 (0.96) | ALDH1A1HSD17B10TDP1TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27836169 | 0.78 | ALDH1A1 (0.96) | ALDH1A1HSD17B10TDP1TSHRSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL8944844 | 0.78 | ALDH1A1 (0.96) | ALDH1A1HSD17B10TDP1TSHRSMN1; SMN2 | |
| SCHEMBL28207718 | 0.78 | ALDH1A1 (0.96) | ALDH1A1HSD17B10TDP1TSHRSMN1; SMN2 | |
| Water SCHEMBL27605675 | 0.78 | ALDH1A1 (0.96) | ALDH1A1HSD17B10TDP1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507616-B1 | Process for the preparation of trisubstituted ureas by reductive carbonylation | ARCO CHEM TECH (US) | 1996-02-07 | — | — | EP | claimed |