Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972648 | 0.94 | AVPR2 (0.49) | AVPR2TP53AVPR1AAVPR1BPDCD1 | |
| SCHEMBL6960384 | 0.91 | AVPR2 (0.43) | AVPR2TP53RAB9AAVPR1AAVPR1B | |
| SCHEMBL6972403 | 0.90 | AVPR2 (0.44) | AVPR2TP53RAB9AAVPR1AAVPR1B | |
| SCHEMBL6969281 | 0.90 | AVPR1A (0.51) | AVPR2TP53GAAAVPR1AAVPR1B | |
| SCHEMBL6955558 | 0.88 | AVPR2 (0.50) | AVPR2AVPR1AOXTR | |
| SCHEMBL6970615 | 0.85 | AVPR1A (0.48) | AVPR2TP53AVPR1A | |
| SCHEMBL6972149 | 0.85 | AVPR2 (0.45) | AVPR2TP53AVPR1AAVPR1BLMNA | |
| SCHEMBL6972475 | 0.84 | AVPR2 (0.48) | AVPR2AVPR1AAVPR1BPDCD1CD274 | |
| SCHEMBL6967250 | 0.84 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6960071 | 0.83 | AVPR1A (0.53) | AVPR2AVPR1AAVPR1BPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |