Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PDE6D | O43924 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961853 | 0.97 | THRB (0.62) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL8961917 | 0.94 | THRB (0.71) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL13899190 | 0.92 | THRB (0.69) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL29315964 | 0.91 | THRB (0.52) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL29315969 | 0.87 | TSHR (0.51) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL991327 | 0.86 | THRB (0.50) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL14408201 | 0.86 | THRB (0.54) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL69211 | 0.85 | THRB (0.84) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL29315967 | 0.85 | THRB (0.59) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL13899156 | 0.84 | THRB (0.55) | THRBTSHRALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488089-A | Curable resin composition | KANSAI PAINT CO., LTD. (JP) | 1996-01-30 | — | — | US | disclosed |