Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 7/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961864 | 0.89 | MEN1 (0.50) | KMT2ALMNAMEN1TP53CYP3A4 | |
| SCHEMBL9809597 | 0.80 | MAOB (0.47) | TP53CYP3A4MAPTKDM4EALDH1A1 | |
| SCHEMBL8961870 | 0.78 | CA9 (0.53) | KMT2ALMNAMEN1TP53CYP3A4 | |
| SCHEMBL8962005 | 0.78 | MAOB (0.53) | KMT2ASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL6891938 | 0.74 | KMT2A (0.48) | KMT2AMEN1CYP3A4MAPTSMN1; SMN2 | |
| 7-Isopropoxycoumarin SCHEMBL14329508 | 0.72 | KDM4E (0.69) | KMT2ATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL6594575 | 0.70 | KDM4E (0.45) | KMT2ALMNAMEN1TP53CYP3A4 | |
| SCHEMBL31222311 | 0.69 | SLC16A3 (0.74) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8961843 | 0.68 | CA12 (0.60) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL9826401 | 0.68 | TP53 (0.47) | KMT2ALMNAMEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586960-B1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA SPA (IT) | 1996-02-07 | — | — | EP | claimed |