Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 6/20 | 0.53 |
| ▸ | CA12 | O43570 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA6 | P23280 | 3/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA5A | P35218 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961864 | 0.88 | MEN1 (0.50) | CA9CA12MAPTSMN1; SMN2KDM4E | |
| SCHEMBL8961843 | 0.86 | CA12 (0.60) | CA9CA12CA1CA6CA7 | |
| SCHEMBL8961920 | 0.78 | KMT2A (0.48) | CA9CA12MAPTSMN1; SMN2KDM4E | |
| SCHEMBL8961835 | 0.72 | ALDH1A1 (0.58) | CA9CA12CA1CA6CA7 | |
| 7-Propoxycoumarin SCHEMBL6690398 | 0.70 | CA9 (1.00) | CA9CA12CA1CA6CA7 | |
| SCHEMBL18474355 | 0.69 | CA9 (0.65) | CA9CA12CA1CA6CA7 | |
| SCHEMBL16674827 | 0.69 | MAOB (0.69) | CA9CA12CA1CA6CA7 | |
| SCHEMBL19025085 | 0.68 | CA9 (0.55) | CA9CA12CA1CA6CA7 | |
| SCHEMBL18474356 | 0.67 | CA12 (0.62) | CA9CA12CA1CA6CA7 | |
| SCHEMBL15968696 | 0.67 | SHBG (0.63) | CA9CA12CA1CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586960-B1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA SPA (IT) | 1996-02-07 | — | — | EP | claimed |