Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | CDC25B | P30305 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11962221 | 0.85 | GAA (0.85) | GAAMEN1KMT2ATDP1MAPT | |
| SCHEMBL14542759 | 0.85 | MAPT (0.59) | GAAMEN1KMT2ATDP1MAPT | |
| SCHEMBL27676838 | 0.85 | GAA (0.59) | GAAMEN1KMT2ATDP1MAPT | |
| SCHEMBL1555794 | 0.82 | GAA (0.55) | GAAMEN1KMT2ATDP1MAPT | |
| SCHEMBL28857668 | 0.79 | MAPT (0.52) | GAAMEN1KMT2ATDP1MAPT | |
| Hydrochloric Acid SCHEMBL27576854 | 0.79 | TDP1 (0.44) | GAAMEN1KMT2ATDP1MAPT | |
| Hydrochloric Acid SCHEMBL4638633 | 0.79 | TDP1 (0.44) | GAAMEN1KMT2ATDP1MAPT | |
| SCHEMBL11883944 | 0.79 | MEN1 (0.74) | GAAMEN1KMT2ATDP1MAPT | |
| SCHEMBL30997736 | 0.79 | MEN1 (0.74) | GAAMEN1KMT2ATDP1MAPT | |
| SCHEMBL6404861 | 0.78 | MEN1 (1.00) | GAAMEN1KMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512950-B1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA GEIGY AG (CH) | 1996-01-17 | — | — | EP | claimed |
| EP-0512950-A1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | claimed |
| EP-0512950-B1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA GEIGY AG (CH) | 1996-01-17 | — | — | EP | disclosed |
| US-5244953-A | Polymers, oxidation and heat resistance | CIBA-GEIGY CORPORATION (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0512950-A1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | disclosed |
| US-5160647-A | High temperature lubricants, heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1992-11-03 | — | — | US | disclosed |