SCHEMBL6404861

SCHEMBL6404861

c1ccc(Nc2cccc3c(Nc4ccccc4)cccc23)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
MAPT P10636 4/20 1.00
TDP1 Q9NUW8 4/20 1.00
GAA P10253 3/20 1.00
KDM4E B2RXH2 3/20 1.00
GLA P06280 1/20 1.00
RECQL P46063 1/20 1.00
ALDH1A1 P00352 6/20 0.78
CDC25B P30305 6/20 0.78
HSD17B10 Q99714 3/20 0.78
HPGD P15428 2/20 0.78
ATM Q13315 2/20 0.78
ALOX15 P16050 2/20 0.78
TSHR P16473 2/20 0.78
TP53 P04637 1/20 0.78
CYP3A4 P08684 1/20 0.78
POLB P06746 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
LMNA P02545 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11962221 0.92 GAA (0.85) MEN1KMT2AMAPTTDP1GAA
SCHEMBL19796 0.88 ALDH1A1 (1.00) MEN1KMT2AMAPTTDP1GAA
SCHEMBL29350230 0.88 ALDH1A1 (1.00) MEN1KMT2AMAPTTDP1GAA
SCHEMBL11802760 0.87 MEN1 (0.76) MEN1KMT2AMAPTTDP1GAA
SCHEMBL22251521 0.87 GAA (0.76) MEN1KMT2AMAPTTDP1GAA
SCHEMBL23589396 0.87 MEN1 (0.76) MEN1KMT2AMAPTTDP1GAA
SCHEMBL11809694 0.87 MEN1 (0.76) MEN1KMT2AMAPTTDP1GAA
Ammonia Solution, Strong SCHEMBL20918916 0.86 ALDH1A1 (0.96) MEN1KMT2AMAPTTDP1GAA
Diphenylamine SCHEMBL1072941 0.86 ALDH1A1 (0.96) MEN1KMT2AMAPTTDP1GAA
Hydrochloric Acid SCHEMBL7408656 0.86 ALDH1A1 (0.96) MEN1KMT2AMAPTTDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2272894-B1 POLYMER COMPOUND, RETICULATED POLYMER COMPOUND PRODUCED BY CROSSLINKING THE POLYMER COMPOUND, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING MITSUBISHI CHEM CORP (JP) 2016-07-06 EP disclosed
US-8581241-B2 Polymer compound, net-like polymer compound produced by crosslinking the polymer compound, composition for organic electroluminescence element, organic electroluminescence element, organic EL display, and organic EL lighting MITSUBISHI CHEMICAL CORPORATION (JP) 2013-11-12 US disclosed
US-20130020562-A1 POLYMER COMPOUND, NET-LIKE POLYMER COMPOUND PRODUCED BY CROSSLINKING THE POLYMER COMPOUND, COMPOSITION FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING MITSUBISHI CHEMICAL CORPORATION 2013-01-24 US disclosed
US-20110108814-A1 POLYMER COMPOUND, NET-LIKE POLYMER COMPOUND PRODUCED BY CROSSLINKING THE POLYMER COMPOUND, COMPOSITION FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2011-05-12 US disclosed
US-6849345-B2 Organic electroluminescent devices with high luminance EASTMAN KODAK COMPANY (US) 2005-02-01 US disclosed
US-20030129449-A1 Organic electroluminescent devices with high luminance EASTMAN KODAK COMPANY 2003-07-10 US disclosed
EP-1298738-A2 Organic electroluminescent devices with high luminance EASTMAN KODAK COMPANY (US) 2003-04-02 EP disclosed
US-6468675-B1 DIPHENYLAMINO ARYLENE STYRYL DERIVATIVES AS A LUMINESCENT LAYER AND ANAROMATIC TERTIARY TRIAMINO COMPOUND AS A HOLE TRANSPORT MATERIAL IN COMBINATION HAS MUCH HIGHER LUMINANCE THAN ONE WITH A DIAMINE COMPOUND NEC CORPORATION (JP) 2002-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030129449-A1 Organic electroluminescent devices with high luminance ARL1, ALDH1A2, EML4 MEN1 1112/4885KMT2A 815/4885MAPT 3627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.