Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | GALK1 | P51570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7940289 | 0.76 | SMN1; SMN2 (0.54) | MAOBCA9CA1RAB9AKDM4E | |
| SCHEMBL321929 | 0.76 | MAOB (0.47) | MAOBRAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL2209825 | 0.76 | TSHR (0.58) | MAOBCA9CA12TSHRGPR35 | |
| SCHEMBL9160537 | 0.76 | RAB9A (0.47) | MAOBRAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL3338142 | 0.76 | MAOB (0.58) | MAOBCA9CA12TSHRGPR35 | |
| SCHEMBL6859091 | 0.75 | KMT2A (0.45) | MAOBCA9CA12TSHRGPR35 | |
| SCHEMBL10710917 | 0.75 | RAB9A (0.47) | MAOBTSHRRAB9AKDM4EALDH1A1 | |
| SCHEMBL16137357 | 0.74 | MAOB (0.52) | MAOBCA9CA12TSHRGPR35 | |
| SCHEMBL11583278 | 0.74 | CA12 (0.45) | MAOBCA9CA12GPR35CA1 | |
| SCHEMBL28550877 | 0.74 | MAOB (0.49) | MAOBCA9CA12TSHRGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516794-A | FOR THE TREATMENT OF BONE RESORPTION | INVERNI DELLA BEEFA S.P.A. (IT) | 1996-05-14 | — | — | US | disclosed |
| EP-0586960-B1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA SPA (IT) | 1996-02-07 | — | — | EP | disclosed |
| EP-0586960-A1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA S.P.A. (IT) | 1994-03-16 | — | — | EP | disclosed |
| US-4290954-A | ANTIALLERGENS, ANTIANAPHYLACTIC AGENTS, ANALGESICS, ANTIINFLAMMATORY AGENTS | KOWA COMPANY LIMITED (JP) | 1981-09-22 | — | — | US | disclosed |
| US-4250182-A | Pharmaceutical composition containing acridone compounds and method of using same | BURROUGHS WELLCOME CO. (US) | 1981-02-10 | — | — | US | disclosed |