SCHEMBL8962153

SCHEMBL8962153

CCCCCCCCOc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.64
FAAH O00519 8/20 0.61
NR5A1 Q13285 1/20 0.56
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
UNG P13051 2/20 0.55
TP53 P04637 1/20 0.54
TSHR P16473 1/20 0.54
HRH2 P25021 1/20 0.54
HRH3 Q9Y5N1 1/20 0.54
PLA2G4B P0C869 1/20 0.53
NAMPT P43490 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4398768 1.00 LTA4H (0.64) LTA4HFAAHNR5A1NPC1RAB9A
SCHEMBL8962099 1.00 LTA4H (0.64) LTA4HFAAHNR5A1NPC1RAB9A
SCHEMBL8962156 1.00 LTA4H (0.64) LTA4HFAAHNR5A1NPC1RAB9A
SCHEMBL9478885 1.00 LTA4H (0.64) LTA4HFAAHNR5A1NPC1RAB9A
SCHEMBL8962108 1.00 LTA4H (0.64) LTA4HFAAHNR5A1NPC1RAB9A
SCHEMBL24145746 1.00 LTA4H (0.64) LTA4HFAAHNR5A1NPC1RAB9A
SCHEMBL30682518 0.95 LTA4H (0.58) LTA4HFAAHNR5A1NPC1RAB9A
SCHEMBL8962169 0.95 LTA4H (0.63) LTA4HFAAHNPC1RAB9ATSHR
SCHEMBL8962079 0.93 NR5A1 (0.63) LTA4HFAAHNR5A1NPC1RAB9A
SCHEMBL11470886 0.93 NR5A1 (0.63) LTA4HFAAHNR5A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0512950-B1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA GEIGY AG (CH) 1996-01-17 EP claimed
EP-0512950-A1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA-GEIGY AG (CH) 1992-11-11 EP claimed
US-5160647-A High temperature lubricants, heat and oxidation resistance CIBA-GEIGY CORPORATION (US) 1992-11-03 US claimed
EP-0512950-B1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA GEIGY AG (CH) 1996-01-17 EP disclosed
US-5244953-A Polymers, oxidation and heat resistance CIBA-GEIGY CORPORATION (US) 1993-09-14 US disclosed
EP-0512950-A1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA-GEIGY AG (CH) 1992-11-11 EP disclosed
US-5160647-A High temperature lubricants, heat and oxidation resistance CIBA-GEIGY CORPORATION (US) 1992-11-03 US disclosed
US-4211663-A LUBRICANTS MOBIL OIL CORPORATION (US) 1980-07-08 US disclosed
US-3879307-A Organic compositions containing synergistic antioxidant mixtures MOBIL OIL CORP 1975-04-22 US disclosed