Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | CDC25B | P30305 | 2/20 | 0.63 |
| ▸ | CDC25A | P30304 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770949 | 0.84 | HSD17B10 (0.67) | HSD17B10CDC25BCDC25AALDH1A1POLB | |
| SCHEMBL8964225 | 0.84 | CDC25B (0.77) | HSD17B10CDC25BCDC25AALDH1A1POLB | |
| SCHEMBL7771248 | 0.82 | HSD17B10 (0.62) | HSD17B10CDC25BCDC25AALDH1A1POLB | |
| SCHEMBL9239725 | 0.82 | CDC25B (0.63) | HSD17B10CDC25BCDC25AALDH1A1POLB | |
| SCHEMBL28110045 | 0.80 | AKR1C3 (0.52) | HSD17B10ALDH1A1POLBAKR1C3KDM4E | |
| SCHEMBL2960119 | 0.80 | ALDH1A1 (0.61) | HSD17B10ALDH1A1POLBAKR1C3KDM4E | |
| SCHEMBL3074652 | 0.78 | CDC25B (1.00) | HSD17B10CDC25BCDC25AALDH1A1POLB | |
| SCHEMBL2058645 | 0.78 | CDC25B (1.00) | HSD17B10CDC25BCDC25AALDH1A1POLB | |
| SCHEMBL1538420 | 0.77 | POLB (0.67) | HSD17B10CDC25BCDC25AALDH1A1POLB | |
| SCHEMBL8417273 | 0.76 | CDC25A (0.62) | HSD17B10CDC25BCDC25AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |