Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.68 |
| ▸ | APEX1 | P27695 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP12 | P39900 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MMP14 | P50281 | 2/20 | 0.47 |
| ▸ | MMP16 | P51512 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10450773 | 0.87 | POLB (0.88) | POLBAPEX1L3MBTL1CTDSP1PKM | |
| SCHEMBL8962231 | 0.86 | POLB (0.56) | POLBAPEX1L3MBTL1CTDSP1KDM4E | |
| SCHEMBL8999902 | 0.86 | APEX1 (0.70) | POLBAPEX1L3MBTL1CTDSP1PKM | |
| SCHEMBL11583247 | 0.84 | POLB (0.51) | POLBAPEX1L3MBTL1CTDSP1PKM | |
| SCHEMBL29364883 | 0.84 | APEX1 (0.67) | POLBAPEX1L3MBTL1CTDSP1GAA | |
| SCHEMBL65212 | 0.84 | APEX1 (0.67) | POLBAPEX1L3MBTL1CTDSP1GAA | |
| SCHEMBL29394064 | 0.84 | APEX1 (0.67) | POLBAPEX1L3MBTL1CTDSP1GAA | |
| SCHEMBL1397921 | 0.84 | APEX1 (0.67) | POLBAPEX1L3MBTL1CTDSP1GAA | |
| SCHEMBL8962127 | 0.83 | APEX1 (0.63) | POLBAPEX1L3MBTL1CTDSP1GAA | |
| SCHEMBL268999 | 0.82 | APEX1 (0.65) | POLBAPEX1L3MBTL1CTDSP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |