Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.50 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.50 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.50 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962292 | 0.86 | POLB (0.68) | POLBAPEX1CTDSP1L3MBTL1AKR1C3 | |
| SCHEMBL8999887 | 0.84 | APEX1 (0.59) | POLBAPEX1CTDSP1L3MBTL1KDM4E | |
| SCHEMBL11704023 | 0.83 | POLB (0.49) | POLBAPEX1CTDSP1L3MBTL1AKR1C3 | |
| SCHEMBL3151230 | 0.82 | MTNR1B (0.56) | MTNR1BABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL31352975 | 0.82 | MTNR1B (0.56) | MTNR1BABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7631413 | 0.82 | POLB (0.62) | POLBAPEX1CTDSP1L3MBTL1AKR1C3 | |
| SCHEMBL11777522 | 0.82 | AKR1C3 (0.51) | POLBL3MBTL1AKR1C3AKR1C2KDM4E | |
| SCHEMBL8962244 | 0.81 | POLB (0.52) | POLBAPEX1CTDSP1L3MBTL1MTNR1B | |
| SCHEMBL5426543 | 0.81 | APEX1 (0.64) | POLBAPEX1CTDSP1L3MBTL1KDM4E | |
| SCHEMBL14282636 | 0.81 | PGR (0.56) | MTNR1BABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |