Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033451 | 0.82 | HTR6 (0.45) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL5860304 | 0.80 | HTR6 (0.49) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL5031550 | 0.79 | HTR6 (0.43) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL9636599 | 0.77 | HTR6 (0.46) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL30307421 | 0.74 | HTR6 (0.44) | HTR6SIGMAR1HTR2AKDM4EHSD17B10 | |
| SCHEMBL31124932 | 0.74 | HTR6 (0.44) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL1539652 | 0.74 | HTR6 (0.44) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL4473077 | 0.72 | HTR6 (0.45) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL1453509 | 0.71 | HTR6 (0.58) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL671513 | 0.70 | HTR6 (0.46) | HTR6SIGMAR1HTR2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500005-B1 | Process for the preparation of substituted indenes | HOECHST AG (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-5194619-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED INDENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0500005-A1 | Process for the preparation of substituted indenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-26 | — | — | EP | disclosed |