Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321851 | 0.74 | KMT2A (0.55) | KMT2A | |
| SCHEMBL856209 | 0.74 | CYP3A4 (0.57) | KMT2A | |
| SCHEMBL9651520 | 0.73 | KMT2A (0.51) | KMT2A | |
| SCHEMBL7574611 | 0.72 | PKM (0.52) | SOAT1 | |
| SCHEMBL9061498 | 0.71 | TRPV1 (0.38) | SOAT1TRPV1 | |
| SCHEMBL8962527 | 0.71 | — | — | |
| SCHEMBL8962355 | 0.71 | — | — | |
| SCHEMBL8962505 | 0.71 | — | — | |
| SCHEMBL8962767 | 0.71 | — | — | |
| SCHEMBL8962555 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019446-A1 | β-CARBOXY SULFONAMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | claimed |
| US-5491170-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-02-13 | — | — | US | claimed |