Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.75 |
| ▸ | CES1 | P23141 | 1/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TDP2 | O95551 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181572 | 0.98 | CES2 (0.78) | CES2CES1TP53TSHRALDH1A1 | |
| SCHEMBL11295596 | 0.94 | TP53 (0.71) | CES2CES1TP53TSHRALDH1A1 | |
| SCHEMBL8962651 | 0.93 | CES2 (0.66) | CES2CES1TP53TSHRALDH1A1 | |
| SCHEMBL333455 | 0.92 | TP53 (0.73) | CES2CES1TP53TSHRALDH1A1 | |
| SCHEMBL11593026 | 0.92 | CES2 (0.76) | CES2CES1TP53TSHRALDH1A1 | |
| Iodide SCHEMBL28290571 | 0.91 | TP53 (0.71) | CES2CES1TP53TSHRALDH1A1 | |
| Hydrogen Sulfide SCHEMBL27626885 | 0.91 | TP53 (0.71) | CES2CES1TP53TSHRALDH1A1 | |
| Benzene SCHEMBL28121215 | 0.91 | TP53 (0.71) | CES2CES1TP53TSHRALDH1A1 | |
| SCHEMBL3234327 | 0.91 | CES2 (0.68) | CES2CES1TP53TSHRALDH1A1 | |
| Bicarbonate SCHEMBL27282989 | 0.91 | TP53 (0.71) | CES2CES1TP53TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474501-B1 | Aromatic diamine compound, preparation process of same and polyimide prepared from same | MITSUI TOATSU CHEMICALS (JP) | 1996-02-14 | — | — | EP | claimed |
| EP-0474501-A1 | Aromatic diamine compound, preparation process of same and polyimide prepared from same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-03-11 | — | — | EP | claimed |
| JP-4338367-A | — | — | None | — | — | JP | disclosed |
| EP-0474501-B1 | Aromatic diamine compound, preparation process of same and polyimide prepared from same | MITSUI TOATSU CHEMICALS (JP) | 1996-02-14 | — | — | EP | disclosed |
| US-5322962-A | Produce polyimides with high heat and chemical resistance, processability | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-06-21 | — | — | US | disclosed |
| US-5231160-A | AROMATIC DIAMINE COMPOUND, PREPARATION PROCESS OF SAME AND POLYIMIDE PREPARED FROM SAME | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-07-27 | — | — | US | disclosed |
| JP-H04338367-A | PRODUCTION OF 1,3-BIS(3-AMINOBENZOYL)BENZENE | MITSUI TOATSU CHEM INC | 1992-11-25 | — | — | JP | disclosed |
| EP-0474501-A1 | Aromatic diamine compound, preparation process of same and polyimide prepared from same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-4352942-A | TREATMENT OF ISOMERIC MIXTURE OF NITRO AROMATIC KETO COMPOUNDS WITH OLEUM | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-10-05 | — | — | US | disclosed |