SCHEMBL8962576

SCHEMBL8962576

C=C(CCCC)C(=O)OCC[Si](C)(C)Cl

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.34
TP53 P04637 1/20 0.34
DGKA P23743 1/20 0.33
ACHE P22303 8/20 0.33
HPGD P15428 1/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
THRB P10828 1/20 0.32
ATM Q13315 1/20 0.31
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8962431 0.92 TSHR (0.44) TSHRALDH1A1TP53DGKAACHE
SCHEMBL8962539 0.83 THRB (0.35) TSHRTHRB
SCHEMBL170886 0.82 TSHR (0.52) TSHRALDH1A1TP53DGKAACHE
SCHEMBL3477341 0.81 TSHR (0.50) TSHRALDH1A1TP53DGKAACHE
SCHEMBL5167857 0.81 TSHR (0.60) TSHRALDH1A1DGKAACHEHPGD
SCHEMBL3081526 0.81 TSHR (0.55) TSHRALDH1A1TP53DGKAACHE
SCHEMBL29168696 0.79 TSHR (0.53) TSHRALDH1A1TP53DGKAACHE
Ethylene SCHEMBL27507038 0.79 TSHR (0.53) TSHRALDH1A1TP53DGKAACHE
SCHEMBL3478206 0.79 TSHR (0.63) TSHRALDH1A1TP53DGKAHPGD
SCHEMBL3477186 0.78 TSHR (0.67) TSHRALDH1A1DGKAACHENAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5554706-A LOW TEMPERATURE LIQUID CRYSTALS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-09-10 US disclosed
EP-0695770-A1 COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-02-07 EP disclosed