Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962622 | 1.00 | AOC3 (0.32) | AOC3HSD11B1MTNR1AMTNR1BSTAT1 | |
| SCHEMBL8962894 | 0.86 | KDR (0.36) | — | |
| SCHEMBL8962664 | 0.84 | HDAC1 (0.32) | — | |
| SCHEMBL8962673 | 0.84 | HDAC1 (0.32) | — | |
| SCHEMBL8962855 | 0.82 | CYP1A2 (0.33) | — | |
| SCHEMBL8962861 | 0.82 | CYP1A2 (0.33) | — | |
| SCHEMBL8963386 | 0.81 | PDE10A (0.33) | — | |
| SCHEMBL8963391 | 0.81 | PDE10A (0.33) | — | |
| SCHEMBL9300037 | 0.80 | — | — | |
| SCHEMBL8962773 | 0.80 | PDE10A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |