Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963391 | 1.00 | PDE10A (0.33) | PDE10AMAPK1 | |
| SCHEMBL8962996 | 0.84 | LRRK2 (0.36) | — | |
| SCHEMBL6879913 | 0.82 | MAPK1 (0.39) | PDE10AMAPK1 | |
| SCHEMBL8962927 | 0.81 | PDE8B (0.31) | PDE10A | |
| SCHEMBL8962618 | 0.81 | AOC3 (0.32) | — | |
| SCHEMBL8962934 | 0.81 | PDE8B (0.31) | PDE10A | |
| SCHEMBL8962622 | 0.81 | AOC3 (0.32) | — | |
| SCHEMBL8963097 | 0.81 | HDAC4 (0.31) | — | |
| SCHEMBL8963086 | 0.81 | HDAC4 (0.31) | — | |
| SCHEMBL8963185 | 0.79 | NPC1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |