⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247546 | 0.90 | LMNA (0.30) | — | |
| SCHEMBL7052168 | 0.90 | LMNA (0.30) | — | |
| SCHEMBL1280244 | 0.87 | LMNA (0.35) | — | |
| SCHEMBL3209467 | 0.87 | LMNA (0.35) | — | |
| SCHEMBL9556712 | 0.87 | LMNA (0.35) | — | |
| SCHEMBL7051335 | 0.82 | — | — | |
| SCHEMBL5159854 | 0.76 | MEN1 (0.38) | — | |
| SCHEMBL5025386 | 0.74 | — | — | |
| SCHEMBL10608682 | 0.74 | MEN1 (0.36) | — | |
| SCHEMBL10354612 | 0.73 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513309-B2 | Perfluorocarbons for use in treating pruritus | OXYGEN BIOTHERAPEUTICS, INC. (US) | 2013-08-20 | — | — | US | claimed |
| US-20120083510-A1 | PERFLUOROCARBONS FOR USE IN TREATING PRURITUS | TENAX THERAPEUTICS, INC | 2012-04-05 | — | — | US | claimed |
| US-8513309-B2 | Perfluorocarbons for use in treating pruritus | OXYGEN BIOTHERAPEUTICS, INC. (US) | 2013-08-20 | — | — | US | disclosed |
| US-20120083510-A1 | PERFLUOROCARBONS FOR USE IN TREATING PRURITUS | TENAX THERAPEUTICS, INC | 2012-04-05 | — | — | US | disclosed |