Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962860 | 1.00 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL8963249 | 0.92 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL8963240 | 0.92 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL8963402 | 0.85 | MEN1 (0.37) | OPRL1 | |
| SCHEMBL9301225 | 0.84 | MAPT (0.37) | OPRL1 | |
| SCHEMBL9300950 | 0.82 | HDAC4 (0.31) | — | |
| SCHEMBL9300956 | 0.82 | HDAC4 (0.31) | — | |
| SCHEMBL9299840 | 0.82 | CYP2C9 (0.39) | OPRL1 | |
| SCHEMBL8962720 | 0.80 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL9300714 | 0.79 | OPRL1 (0.31) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0559860-A1 | HALOVINYL-DERIVATIVES. | HOFFMANN LA ROCHE (CH) | 1993-09-15 | — | — | EP | disclosed |
| WO-1993007234-A1 | HALOVINYL-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-15 | — | — | WO | disclosed |