Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27393398 | 0.85 | ACHE (0.43) | ACHESMN1; SMN2MAPK1LMNAMGAM | |
| SCHEMBL590531 | 0.81 | EPHX1 (0.53) | ACHERAB9ATSHREPHX1NPSR1 | |
| SCHEMBL697911 | 0.80 | — | — | |
| SCHEMBL12487443 | 0.79 | ACHE (0.35) | ACHESMN1; SMN2CHRM2CHRM4CHRM5 | |
| SCHEMBL9459327 | 0.78 | EPHX1 (0.66) | ACHETSHREPHX1 | |
| SCHEMBL9459137 | 0.78 | EPHX1 (0.66) | ACHETSHREPHX1 | |
| SCHEMBL9459205 | 0.78 | EPHX1 (0.66) | ACHETSHREPHX1 | |
| SCHEMBL9459326 | 0.78 | EPHX1 (0.66) | ACHETSHREPHX1 | |
| SCHEMBL27904990 | 0.78 | MAPT (0.42) | ACHESMN1; SMN2NPC1RAB9ACYP2D6 | |
| SCHEMBL1607872 | 0.74 | CRBN (0.39) | ACHESMN1; SMN2RAB9ATSHRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451953-B1 | Process for the preparation of polyether amides from mixed amines | HUNTSMAN CORP (US) | 1996-02-14 | — | — | EP | disclosed |
| US-5118785-A | PREPARATION OF POLYETHER AMIDE FROM TETRAETHYLENE GLYCOL DIAMINE AND TEREPHTHALIC ACID | TEXACO CHEMICAL COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0451951-A2 | Polyether amide from tetraethylene glycol diamine and terephthalic acid | TEXACO CHEMICAL COMPANY (US) | 1991-10-16 | — | — | EP | disclosed |
| EP-0451953-A2 | Process for the preparation of polyether amides from mixed amines | Huntsman Corporation (US) | 1991-10-16 | — | — | EP | disclosed |
| US-5053484-A | POLYETHER AMIDE FROM MIXTURE OF POLYETHER DIAMINE | TEXACO CHEMICAL COMPANY (US) | 1991-10-01 | — | — | US | disclosed |