Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963199 | 1.00 | CSF1R (0.38) | CSF1RMEN1KMT2AL3MBTL1AVPR1A | |
| SCHEMBL8963209 | 0.90 | CSF1R (0.35) | CSF1RMEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL8963204 | 0.90 | CSF1R (0.35) | CSF1RMEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL8963068 | 0.87 | MEN1 (0.35) | CSF1RMEN1KMT2AL3MBTL1PDE10A | |
| SCHEMBL8963073 | 0.87 | MEN1 (0.35) | CSF1RMEN1KMT2AL3MBTL1PDE10A | |
| SCHEMBL8963379 | 0.85 | PDE10A (0.37) | CSF1RMEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL8963382 | 0.85 | PDE10A (0.37) | CSF1RMEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL8962756 | 0.83 | SMN1; SMN2 (0.35) | CSF1RMEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL8962748 | 0.83 | SMN1; SMN2 (0.35) | CSF1RMEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL8963235 | 0.83 | AVPR1A (0.31) | AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |