Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963269 | 1.00 | MAOB (0.44) | MAOBGPR84S1PR1S1PR5P2RX3 | |
| SCHEMBL9450829 | 0.95 | MAOB (0.40) | MAOBGPR84S1PR1S1PR5P2RX3 | |
| SCHEMBL8963138 | 0.89 | MAOB (0.44) | MAOBGPR84S1PR1S1PR5HRH3 | |
| SCHEMBL8963130 | 0.89 | MAOB (0.44) | MAOBGPR84S1PR1S1PR5HRH3 | |
| SCHEMBL8962736 | 0.89 | GPR84 (0.36) | MAOBGPR84S1PR1S1PR5HRH3 | |
| SCHEMBL8962731 | 0.89 | GPR84 (0.36) | MAOBGPR84S1PR1S1PR5HRH3 | |
| SCHEMBL8963373 | 0.87 | MAOB (0.45) | MAOBGPR84MAOATAAR1 | |
| SCHEMBL8963369 | 0.87 | MAOB (0.45) | MAOBGPR84MAOATAAR1 | |
| SCHEMBL8962925 | 0.86 | GPR84 (0.36) | MAOBGPR84MAOATAAR1 | |
| SCHEMBL8963039 | 0.86 | MAOB (0.44) | MAOBGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |