⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95036 | 0.91 | — | — | |
| SCHEMBL217920 | 0.88 | CES2 (0.62) | — | |
| SCHEMBL78734 | 0.88 | CES2 (0.62) | — | |
| SCHEMBL76015 | 0.88 | CES2 (0.62) | — | |
| SCHEMBL6755768 | 0.88 | CES2 (0.62) | — | |
| SCHEMBL5510390 | 0.88 | CES2 (0.62) | — | |
| SCHEMBL216281 | 0.88 | CES2 (0.62) | — | |
| SCHEMBL218241 | 0.88 | CES2 (0.62) | — | |
| SCHEMBL217644 | 0.88 | CES2 (0.62) | — | |
| SCHEMBL42015 | 0.88 | CES2 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4075 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11866518-B2 | Bicyclic peptide ligands specific for TSLP | BICYCLETX LIMITED (GB) | 2024-01-09 | — | — | US | claimed |
| CN-115768456-A | TSLP-specific bicyclic peptide ligands | 拜斯科技术开发有限公司 | 2023-03-07 | — | — | CN | claimed |
| EP-4132481-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TSLP | BicycleTX Limited (GB) | 2023-02-15 | — | — | EP | claimed |
| CN-115611814-A | Compound containing 2-aminoimidazole ring and preparation method and application thereof | 烟台新药创制山东省实验室 | 2023-01-17 | — | — | CN | claimed |
| US-20220363718-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TSLP | BICYCLETX LIMITED (GB) | 2022-11-17 | — | — | US | claimed |
| EP-4008717-A2 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | claimed |
| EP-4008716-A1 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | claimed |
| CN-109912458-B | Metal halide perovskite material, preparation method thereof, solar cell device and preparation method thereof | 苏州大学 | 2022-01-04 | — | — | CN | claimed |
| EP-3924349-A2 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | The Roskamp Institute (US) | 2021-12-22 | — | — | EP | claimed |
| CN-110256432-A | Inhibit the polycyclic compound of MNK1 and MNK2 | 诺沃斯达药业有限公司 | 2019-09-20 | — | — | CN | claimed |
| EP-0686872-A1 | Silver halide light-sensitive color photographic material | KONICA CORPORATION (JP) | 1995-12-13 | — | — | EP | claimed |
| US-5466823-A | Antiinflammatory agents; FDA Orange book listed patent for Celebrex | G.D. SEARLE & CO. (US) | 1995-11-14 | — | — | US | claimed |
| EP-0247482-B1 | HARDENED REAGENT COATINGS, AND PROCESSES FOR THE PREPARATION THEREOF | MILES INC. (US) | 1992-04-22 | — | — | EP | claimed |
| US-4832733-A | 3-amino-2-cyano-acrylic acid ester herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-23 | — | — | US | claimed |
| US-4801706-A | ANTIARRHYTHMIA HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-01-31 | — | — | US | claimed |
| CN-88103601-A | N-PHENYLPYRAZOLE DERIVATIVES | — | 1988-12-28 | — | — | CN | claimed |
| EP-0241826-A1 | 3-Amino-2-cyano-acrylic acid esters | BAYER AG (DE) | 1987-10-21 | — | — | EP | claimed |
| US-4196291-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1980-04-01 | — | — | US | claimed |
| US-4141978-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-02-27 | — | — | US | claimed |
| US-4001411-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-01-04 | — | — | US | claimed |