Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8964156 | 0.99 | PRMT5 (0.37) | PRMT5NPY5RHPGDSPIN1HTR6 | |
| Hydrochloric Acid SCHEMBL8963711 | 0.94 | PRMT5 (0.34) | PRMT5NPY5RHPGDSPIN1HTR6 | |
| Hydrochloric Acid SCHEMBL8963446 | 0.92 | PRMT5 (0.36) | PRMT5NPY5RHTR6DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8963722 | 0.92 | PRMT5 (0.33) | PRMT5NPY5RHPGDSPIN1HTR6 | |
| Hydrochloric Acid SCHEMBL8963626 | 0.92 | CETP (0.36) | PRMT5NPY5RHPGDSDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8963781 | 0.91 | PIN1 (0.35) | PRMT5NPY5RHPGDSPIN1HTR6 | |
| Hydrochloric Acid SCHEMBL8963985 | 0.91 | HDAC6 (0.37) | PRMT5OPRD1 | |
| Hydrochloric Acid SCHEMBL8964131 | 0.91 | PDE2A (0.38) | PRMT5NPY5RHPGDSOPRD1 | |
| Hydrochloric Acid SCHEMBL8963755 | 0.91 | PIN1 (0.39) | PRMT5NPY5RPIN1HTR6ADRB1 | |
| Hydrochloric Acid SCHEMBL8963712 | 0.90 | PRMT5 (0.37) | PRMT5NPY5RTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |