Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.73 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.73 |
| ▸ | HRH1 | P35367 | 6/20 | 0.73 |
| ▸ | HRH2 | P25021 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | MIF | P14174 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | APEX1 | P27695 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963886 | 0.89 | HRH3 (0.75) | HRH3HRH4HRH1HRH2LMNA | |
| SCHEMBL8964986 | 0.89 | HRH3 (0.79) | HRH3HRH4HRH1HRH2 | |
| SCHEMBL890317 | 0.87 | — | — | |
| SCHEMBL8963957 | 0.87 | HRH3 (0.80) | HRH3HRH4HRH1HRH2 | |
| SCHEMBL5107846 | 0.85 | — | — | |
| SCHEMBL2006357 | 0.85 | — | — | |
| SCHEMBL16435160 | 0.85 | — | — | |
| Bromide SCHEMBL10400874 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL11356357 | 0.83 | — | — | |
| Histamine SCHEMBL16778301 | 0.83 | HRH3 (1.00) | HRH3HRH4HRH1HRH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525621-A | CARDIOVASCULAR DISORDERS; ANTIINFLAMMATORY AGENTS | CYTOS PHARMACEUTICALS LLC (US) | 1996-06-11 | — | — | US | claimed |
| US-5525621-A | CARDIOVASCULAR DISORDERS; ANTIINFLAMMATORY AGENTS | CYTOS PHARMACEUTICALS LLC (US) | 1996-06-11 | — | — | US | disclosed |