Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.80 |
| ▸ | HRH1 | P35367 | 7/20 | 0.80 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.80 |
| ▸ | HRH2 | P25021 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964986 | 0.97 | HRH3 (0.79) | HRH3HRH1HRH4HRH2 | |
| SCHEMBL8963886 | 0.92 | HRH3 (0.75) | HRH3HRH1HRH4HRH2 | |
| SCHEMBL9220957 | 0.89 | HRH3 (1.00) | HRH3HRH1HRH4HRH2 | |
| SCHEMBL3389071 | 0.89 | HRH3 (0.67) | HRH3HRH1HRH4HRH2 | |
| Impentamine SCHEMBL9221066 | 0.89 | HRH3 (1.00) | HRH3HRH1HRH4HRH2 | |
| SCHEMBL7576395 | 0.89 | HRH3 (0.85) | HRH3HRH1HRH4HRH2 | |
| SCHEMBL6909231 | 0.89 | HRH3 (0.85) | HRH3HRH1HRH4HRH2 | |
| Impentamine SCHEMBL29462290 | 0.88 | HRH3 (1.00) | HRH3HRH1HRH4HRH2 | |
| SCHEMBL8963903 | 0.87 | HRH3 (0.73) | HRH3HRH1HRH4HRH2 | |
| SCHEMBL4687435 | 0.87 | HRH3 (0.66) | HRH3HRH1HRH4HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525621-A | CARDIOVASCULAR DISORDERS; ANTIINFLAMMATORY AGENTS | CYTOS PHARMACEUTICALS LLC (US) | 1996-06-11 | — | — | US | disclosed |