Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8963877 | 0.99 | NPY5R (0.39) | NPY5RHPGDSOPRD1PRMT5POLB | |
| Hydrochloric Acid SCHEMBL8964022 | 0.93 | NPY5R (0.37) | NPY5RHPGDSOPRD1PRMT5POLB | |
| Hydrochloric Acid SCHEMBL8963569 | 0.92 | NPY5R (0.38) | NPY5RHPGDSOPRD1POLBDRD2 | |
| Hydrochloric Acid SCHEMBL8963546 | 0.92 | MAPK13 (0.36) | NPY5RHPGDSOPRD1PRMT5POLB | |
| Hydrochloric Acid SCHEMBL8963925 | 0.92 | HDAC6 (0.39) | NPY5RHPGDSOPRD1PRMT5HPGD | |
| Hydrochloric Acid SCHEMBL8963652 | 0.92 | OPRD1 (0.38) | NPY5RHPGDSOPRD1PRMT5POLB | |
| Hydrochloric Acid SCHEMBL8963768 | 0.92 | NPY5R (0.38) | NPY5ROPRD1PRMT5MAPK13MAPK12 | |
| Hydrochloric Acid SCHEMBL8963764 | 0.91 | MAPK14 (0.36) | NPY5RHPGDSOPRD1PRMT5PIN1 | |
| Hydrochloric Acid SCHEMBL8963504 | 0.90 | PRMT5 (0.40) | NPY5RPRMT5KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8963586 | 0.90 | NPY5R (0.40) | NPY5RPRMT5KMT2AMEN1SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |