Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10357466 | 1.00 | TSHR (0.50) | TSHRGAACYP1A2HPGDALDH1A1 | |
| SCHEMBL21891714 | 0.94 | GAA (0.56) | TSHRGAACYP1A2HPGDALDH1A1 | |
| SCHEMBL5127220 | 0.87 | TP53 (0.59) | TSHRGAACYP1A2HPGDALDH1A1 | |
| SCHEMBL8659026 | 0.86 | TP53 (0.64) | GAAHPGDALDH1A1TP53NPC1 | |
| Phthalic Acid SCHEMBL8161821 | 0.85 | ALDH1A1 (0.52) | TSHRGAAALDH1A1KDM4EPOLB | |
| SCHEMBL9091405 | 0.85 | TSHR (0.48) | TSHRGAACYP1A2HPGDALDH1A1 | |
| SCHEMBL9092439 | 0.85 | TSHR (0.48) | TSHRGAACYP1A2HPGDALDH1A1 | |
| SCHEMBL8963512 | 0.85 | TSHR (0.48) | TSHRGAACYP1A2HPGDALDH1A1 | |
| Phthalic Acid SCHEMBL29793929 | 0.83 | ALDH1A1 (0.64) | TSHRALDH1A1TP53KDM4ELMNA | |
| Phthalic Acid SCHEMBL28653607 | 0.83 | ALDH1A1 (0.64) | TSHRALDH1A1TP53KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4780319-A | DRUG DELIVERY USING POLYORTHOESTERS COATINGS | MERCK & CO., INC. (US) | 1988-10-25 | — | — | US | claimed |
| EP-0705591-A2 | Cyclic amidocarboxy surfactants, synthesis and use thereof | STEPAN COMPANY (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0486510-B1 | CYCLIC AMIDOCARBOXY SURFACTANTS, SYNTHESIS AND USE THEREOF | STEPAN CO (US) | 1996-02-14 | — | — | EP | disclosed |
| EP-0688601-A1 | Cyclic amidocarboxy surfactants, synthesis and use thereof | STEPAN COMPANY (US) | 1995-12-27 | — | — | EP | disclosed |
| EP-0486510-A1 | CYCLIC AMIDOCARBOXY SURFACTANTS, SYNTHESIS AND USE THEREOF. | STEPAN CO (US) | 1992-05-27 | — | — | EP | disclosed |
| WO-1991001970-A2 | CYCLIC AMIDOCARBOXY SURFACTANTS, SYNTHESIS AND USE THEREOF | STEPAN COMPANY (US) | 1991-02-21 | — | — | WO | disclosed |
| EP-0208617-B1 | CONTROLLED DRUG DEVICE AND PROCESS FOR CATALYSING THE EROSION OF AN ACID LABILE POLYMER | MERCK & CO. INC. (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4780319-A | DRUG DELIVERY USING POLYORTHOESTERS COATINGS | MERCK & CO., INC. (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0208617-A1 | Controlled drug device and process for catalysing the erosion of an acid labile polymer | MERCK & CO. INC. (US) | 1987-01-14 | — | — | EP | disclosed |