Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963978 | 0.99 | NAAA (0.30) | PDE5AHDAC1HDAC6NAAA | |
| SCHEMBL8964276 | 0.96 | RARB (0.32) | RARB | |
| SCHEMBL8964109 | 0.96 | RARB (0.32) | RARB | |
| SCHEMBL8964007 | 0.96 | RARB (0.32) | RARB | |
| SCHEMBL8964248 | 0.96 | RARB (0.32) | RARB | |
| SCHEMBL8964052 | 0.96 | RARB (0.32) | RARB | |
| SCHEMBL8964251 | 0.96 | RARB (0.32) | RARB | |
| SCHEMBL8964070 | 0.96 | RARB (0.32) | RARB | |
| SCHEMBL8964257 | 0.96 | RARB (0.32) | RARB | |
| SCHEMBL8964207 | 0.96 | CCNT1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |