Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879928 | 0.84 | TSHR (0.45) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL29207442 | 0.78 | TSHR (0.42) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL11694160 | 0.77 | TSHR (0.45) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL27988585 | 0.76 | TSHR (0.38) | TSHRHPGD | |
| SCHEMBL28881519 | 0.76 | TSHR (0.44) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL27666160 | 0.76 | TSHR (0.44) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL202442 | 0.75 | — | — | |
| SCHEMBL672062 | 0.74 | TSHR (0.50) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL6275105 | 0.74 | TSHR (0.50) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL4410095 | 0.74 | CTSD (0.41) | TSHRALDH1A1CTSDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0488627-B1 | Oxygen permeable contact lens and method of manufacture therefor | PILKINGTON BARNES HIND INC (US) | 1996-02-14 | — | — | EP | disclosed |
| US-5170192-A | Crosslinked interpenetrating network copolymers; addition polymerization | PILKINGTON VISIONCARE, INC. (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0488627-A2 | Oxygen permeable contact lens and method of manufacture therefor | PARAGON VISION SCIENCES, INC. (US) | 1992-06-03 | — | — | EP | disclosed |