Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3518115 | 1.00 | AGTR2 (1.00) | AGTR2AGTR1 | |
| SCHEMBL8964079 | 0.92 | AGTR2 (1.00) | AGTR2AGTR1 | |
| SCHEMBL8964453 | 0.92 | AGTR2 (1.00) | AGTR2AGTR1 | |
| SCHEMBL9269434 | 0.88 | AGTR2 (0.79) | AGTR2AGTR1 | |
| SCHEMBL23315510 | 0.86 | AGTR2 (0.75) | AGTR2AGTR1 | |
| SCHEMBL23315475 | 0.86 | AGTR2 (0.75) | AGTR2AGTR1 | |
| SCHEMBL3514143 | 0.85 | AGTR2 (0.75) | AGTR2AGTR1 | |
| SCHEMBL21881226 | 0.83 | AGTR2 (0.73) | AGTR2AGTR1 | |
| SCHEMBL21881275 | 0.83 | AGTR2 (0.73) | AGTR2AGTR1 | |
| SCHEMBL23315400 | 0.83 | AGTR2 (0.73) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525614-A | TREATING VASCULAR RESTENOSIS, CNS DISORDERS | WARNER-LAMBERT COMPANY (US) | 1996-06-11 | — | — | US | disclosed |
| US-5489686-A | CARDIOVASCULAR DISORDER, NERVOUS SYSTEM DISORDER, ANTIDIURETIC , PSYCHLOGICAL DISORDER, ANTIDEPRESSANTS | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |
| US-5350757-A | Treatment of vascular restenosis, nervous system disorders and cognition enhancement | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |
| US-5246943-A | Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties | WARNER-LAMBERT COMPANY (US) | 1993-09-21 | — | — | US | disclosed |