SCHEMBL8964844

SCHEMBL8964844

C[CH][Si](CC1=CC2CCC1C2)(OC)OC

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443455 0.71 CYP19A1 (0.31) CYP19A1
SCHEMBL9788868 0.71 CYP19A1 (0.31) CYP19A1
SCHEMBL8964842 0.70 CYP19A1 (0.31) CYP19A1
SCHEMBL9484396 0.68
SCHEMBL10454167 0.68
SCHEMBL239774 0.68
SCHEMBL240511 0.65
SCHEMBL8965491 0.65
SCHEMBL18549845 0.65 CYP19A1 (0.31) CYP19A1
SCHEMBL1978763 0.64 CYP19A1 (0.31) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0539901-B1 Process for producing thermoplastic resin JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-02-28 EP claimed
EP-0539901-A1 Process for producing thermoplastic resin JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-05-05 EP claimed
EP-0539901-B1 Process for producing thermoplastic resin JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-02-28 EP disclosed
US-5274053-A Grafting a vinyl monomer to a modified polyorganosiloxane and crosslinking with an alkoxysilane having an azo or disulfide group JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-12-28 US disclosed
EP-0539901-A1 Process for producing thermoplastic resin JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-05-05 EP disclosed