SCHEMBL9788868

SCHEMBL9788868

CCO[Si](CC1=CC2CCC1C2)(OCC)OCC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5076399 0.84 CYP19A1 (0.30) CYP19A1
SCHEMBL239774 0.74
SCHEMBL8852206 0.72 CYP19A1 (0.35) CYP19A1
SCHEMBL7459517 0.72 CYP19A1 (0.33) CYP19A1
SCHEMBL18929693 0.71 CYP19A1 (0.32) CYP19A1
SCHEMBL8851767 0.71 CYP19A1 (0.35) CYP19A1
SCHEMBL8964844 0.71 CYP19A1 (0.30) CYP19A1
SCHEMBL28268203 0.70
SCHEMBL8505218 0.69 CYP19A1 (0.33) CYP19A1
SCHEMBL155171 0.68 SPHK1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2270888-A None JP disclosed
US-5055499-A Metathesis polymerizing a cyclolefin in the presence of a filler treated with a norbornene-substituted silane coupling agent; boat and automobile reaction injection molded parts; rigidity; impact strength HERCULES INCORPORATED (US) 1991-10-08 US disclosed
EP-0439650-A1 Molded polymer article filled with inorganic material and production of said article HERCULES INCORPORATED (US) 1991-08-07 EP disclosed
JP-H02270888-A NOVEL SILANE COMPOUND TEIJIN LTD 1990-11-05 JP disclosed