Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.61 |
| ▸ | NPC1 | O15118 | 10/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | HPGD | P15428 | 10/20 | 0.61 |
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.61 |
| ▸ | RELA | Q04206 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | STAT1 | P42224 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23079764 | 0.91 | NPC1 (0.52) | ALDH1A1NPC1KDM4EHPGDRAB9A | |
| SCHEMBL24155750 | 0.88 | NPC1 (0.49) | ALDH1A1NPC1KDM4EHPGDRAB9A | |
| SCHEMBL22058290 | 0.86 | ALDH1A1 (0.48) | ALDH1A1NPC1KDM4EHPGDRAB9A | |
| SCHEMBL24155749 | 0.86 | NPC1 (0.47) | ALDH1A1NPC1KDM4EHPGDRAB9A | |
| SCHEMBL24156090 | 0.86 | NPC1 (0.47) | ALDH1A1NPC1KDM4EHPGDRAB9A | |
| SCHEMBL24156150 | 0.86 | NPC1 (0.48) | ALDH1A1NPC1KDM4EHPGDRAB9A | |
| SCHEMBL22746781 | 0.85 | NPC1 (0.47) | ALDH1A1NPC1KDM4EHPGDRAB9A | |
| SCHEMBL22746779 | 0.85 | NPC1 (0.46) | ALDH1A1NPC1KDM4EHPGDRAB9A | |
| SCHEMBL24586964 | 0.83 | NPC1 (0.45) | ALDH1A1NPC1KDM4EHPGDRAB9A | |
| SCHEMBL23079661 | 0.83 | NPC1 (0.52) | ALDH1A1NPC1KDM4EHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |