Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22982168 | 0.86 | ALDH1A1 (0.60) | ALDH1A1TDP1MAPK1POLBTSHR | |
| SCHEMBL11002356 | 0.85 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPK1POLBTSHR | |
| SCHEMBL11002726 | 0.85 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPK1POLBTSHR | |
| SCHEMBL3790125 | 0.84 | ALDH1A1 (0.66) | ALDH1A1TDP1MAPK1POLBTSHR | |
| SCHEMBL27622978 | 0.84 | ALDH1A1 (0.66) | ALDH1A1TDP1MAPK1POLBTSHR | |
| SCHEMBL14655670 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TDP1MAPK1POLBTSHR | |
| SCHEMBL4624403 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TDP1MAPK1POLBTSHR | |
| SCHEMBL10998807 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TDP1MAPK1POLBTSHR | |
| SCHEMBL6285865 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TDP1MAPK1POLBTSHR | |
| SCHEMBL6282840 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TDP1MAPK1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8198844-A | — | — | None | — | — | JP | disclosed |
| CN-106537149-A | Method for screening trp channels | 宝洁公司 | 2017-03-22 | — | — | CN | disclosed |
| JP-H08198844-A | PRODUCTION OF SULFENYLACETIC ACID DERIVATIVE | FUJIREBIO INC | 1996-08-06 | — | — | JP | disclosed |