Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 10/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26136640 | 0.91 | TYR (0.40) | PDK2LMNAMAPTALOX12NPSR1 | |
| SCHEMBL28930025 | 0.90 | PDK2 (0.46) | PDK2APEX1MAPTESR2TYR | |
| SCHEMBL29370881 | 0.84 | APEX1 (0.53) | PDK2APEX1PGRLMNAMAPT | |
| SCHEMBL9867937 | 0.84 | APEX1 (0.53) | PDK2APEX1PGRLMNAMAPT | |
| SCHEMBL1617518 | 0.84 | APEX1 (0.53) | PDK2APEX1PGRLMNAMAPT | |
| SCHEMBL26482127 | 0.83 | APEX1 (0.45) | PDK2APEX1PGR | |
| SCHEMBL9781137 | 0.83 | APEX1 (0.43) | PDK2APEX1PGR | |
| SCHEMBL26135697 | 0.81 | TYR (0.42) | PDK2LMNAMAPTALOX12NPSR1 | |
| SCHEMBL12095465 | 0.80 | PDK2 (0.47) | PDK2APEX1PGRLMNAPOLB | |
| SCHEMBL4341387 | 0.80 | PDK2 (0.47) | PDK2APEX1PGRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |