Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 3/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1617518 | 1.00 | APEX1 (0.53) | APEX1PGRPDK2CYP2D6CYP1A2 | |
| SCHEMBL29370881 | 1.00 | APEX1 (0.53) | APEX1PGRPDK2CYP2D6CYP1A2 | |
| SCHEMBL9781136 | 0.89 | PGR (0.44) | APEX1PGRPDK2CYP2D6CYP1A2 | |
| SCHEMBL28480617 | 0.87 | APEX1 (0.47) | APEX1PGRPDK2CYP2D6CYP1A2 | |
| SCHEMBL17735533 | 0.87 | APEX1 (0.43) | APEX1PGRPDK2CYP2D6CYP1A2 | |
| SCHEMBL9781137 | 0.87 | APEX1 (0.43) | APEX1PGRPDK2 | |
| SCHEMBL1394531 | 0.86 | APEX1 (0.50) | APEX1PGRPDK2CYP2D6CYP1A2 | |
| SCHEMBL30110388 | 0.86 | APEX1 (0.50) | APEX1PGRPDK2CYP2D6CYP1A2 | |
| SCHEMBL17084381 | 0.85 | APEX1 (0.42) | APEX1PGRPDK2 | |
| SCHEMBL83466 | 0.85 | APEX1 (0.48) | APEX1PGRPDK2CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037578-A | Light source excites dyes solution to generate coherent laser radiation | EXCITON CHEMICAL COMPANY (US) | 1991-08-06 | — | — | US | disclosed |