Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965160 | 0.99 | PTGIR (0.60) | PTGIRKMT2AL3MBTL1TBXAS1PTGDR2 | |
| SCHEMBL8966026 | 0.96 | PTGIR (0.61) | PTGIRKMT2AL3MBTL1TBXAS1PTGDR2 | |
| SCHEMBL8965905 | 0.82 | PTGIR (0.52) | PTGIRTBXAS1PTGDR2TBXA2R | |
| SCHEMBL8965065 | 0.81 | PTGIR (0.53) | PTGIRKMT2AL3MBTL1TBXAS1PTGDR2 | |
| SCHEMBL8965375 | 0.79 | PTGDR2 (0.63) | PTGIRPTGDR2 | |
| SCHEMBL8965896 | 0.78 | PTGIR (0.53) | PTGIRTBXAS1PTGDR2TBXA2R | |
| SCHEMBL8354769 | 0.78 | PTGIR (0.55) | PTGIRKMT2APTGDR2 | |
| SCHEMBL8804127 | 0.76 | PTGDR2 (0.67) | PTGIRPTGDR2 | |
| SCHEMBL8965748 | 0.76 | PTGIR (0.57) | PTGIRTBXAS1PTGDR2TBXA2R | |
| SCHEMBL3176262 | 0.75 | PTGDR2 (0.67) | PTGIRKMT2AL3MBTL1TBXAS1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | claimed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | claimed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |