Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.63 |
| ▸ | PTGIR | P43119 | 5/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804127 | 0.97 | PTGDR2 (0.67) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8965139 | 0.93 | PTGDR2 (0.61) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8965905 | 0.89 | PTGIR (0.52) | PTGDR2PTGIRPPARA | |
| SCHEMBL8965728 | 0.88 | PTGDR2 (0.57) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8358402 | 0.87 | PTGDR2 (0.55) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8965035 | 0.86 | PTGDR2 (0.55) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8358618 | 0.86 | PTGIR (0.56) | PTGDR2PTGIRPPARAPPARG | |
| SCHEMBL8965896 | 0.85 | PTGIR (0.53) | PTGDR2PTGIRPPARA | |
| SCHEMBL8965703 | 0.84 | PTGDR2 (0.65) | PTGDR2PTGIRPTGDR | |
| SCHEMBL3180595 | 0.81 | PTGDR2 (0.94) | PTGDR2PTGIRPPARAPPARGPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | claimed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | claimed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |