Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358170 | 0.78 | CYP4F2 (0.48) | CYP4F2CYP4A11MGLLBCHEKMT2A | |
| SCHEMBL3165628 | 0.69 | CYP4F2 (0.81) | CYP4F2CYP4A11MGLLBCHEKMT2A | |
| SCHEMBL8965280 | 0.69 | PTGDR2 (0.55) | KMT2APTGDR2MEN1PKMPTGDR | |
| SCHEMBL5760533 | 0.68 | CYP4F2 (0.79) | CYP4F2CYP4A11MGLLBCHEKMT2A | |
| SCHEMBL8965343 | 0.68 | PTGDR2 (0.56) | PTGDR2LMNAALOX15MAPK1PTGDR | |
| SCHEMBL8965129 | 0.67 | PTGDR2 (0.55) | PTGDR2PTGDR | |
| SCHEMBL8354939 | 0.67 | CYP4F2 (0.48) | CYP4F2CYP4A11MGLLBCHEKMT2A | |
| SCHEMBL3169044 | 0.67 | CYP4F2 (0.66) | CYP4F2CYP4A11MGLLBCHEFFAR1 | |
| SCHEMBL4568936 | 0.67 | CYP4F2 (0.66) | CYP4F2CYP4A11MGLLBCHE | |
| SCHEMBL16493762 | 0.67 | CYP4F2 (0.66) | CYP4F2CYP4A11MGLLBCHEFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |