Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.56 |
| ▸ | PTGIR | P43119 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965898 | 0.92 | PTGDR2 (0.50) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8965284 | 0.92 | PTGDR2 (0.48) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL9539550 | 0.90 | PTGDR2 (0.47) | PTGDR2PTGIRPPARAPPARG | |
| SCHEMBL8358368 | 0.90 | MEN1 (0.47) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8358170 | 0.87 | CYP4F2 (0.48) | PTGDR2PTGDRMAPK1LMNAALOX15 | |
| SCHEMBL8354882 | 0.84 | PPARA (0.55) | PTGDR2PTGIRPPARAPPARG | |
| SCHEMBL8965929 | 0.82 | PTGDR2 (0.61) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8965280 | 0.81 | PTGDR2 (0.55) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8965129 | 0.81 | PTGDR2 (0.55) | PTGDR2PTGIRPPARAPPARGPTGDR | |
| SCHEMBL8358292 | 0.79 | CALM1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | claimed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |