Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.48 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965246 | 0.85 | NPC1 (0.55) | NPC1ALOX5PDE10AAGPAT2PTGS2 | |
| SCHEMBL8965198 | 0.83 | KDM6B (0.48) | NPC1AGPAT2PTGS2L3MBTL1GAA | |
| SCHEMBL5834311 | 0.79 | MAPT (0.53) | NPC1ALOX5AGPAT2PTGS2L3MBTL1 | |
| SCHEMBL12203168 | 0.79 | KMT2A (0.58) | NPC1GAAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL23079758 | 0.77 | NPC1 (0.55) | NPC1L3MBTL1GAAHPSEHPGD | |
| SCHEMBL27049432 | 0.77 | NPC1 (0.55) | NPC1L3MBTL1GAAHPSEHPGD | |
| SCHEMBL27049405 | 0.76 | NPC1 (0.50) | NPC1L3MBTL1GAAHPSEHPGD | |
| SCHEMBL27049425 | 0.76 | NPC1 (0.53) | NPC1L3MBTL1GAAHPSEHPGD | |
| SCHEMBL23079787 | 0.75 | NPC1 (0.58) | NPC1L3MBTL1GAAHPGDKDM4E | |
| SCHEMBL23079822 | 0.75 | NPC1 (0.58) | NPC1L3MBTL1GAAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |