Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 2/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965517 | 0.85 | NPC1 (0.51) | NPC1KDM4EALDH1A1CASP3SENP7 | |
| SCHEMBL8964811 | 0.83 | KDM4E (0.56) | NPC1KDM4EALDH1A1CASP3SENP7 | |
| SCHEMBL28139056 | 0.81 | ELANE (0.69) | NPC1KDM4EALDH1A1CASP3SENP7 | |
| SCHEMBL7735667 | 0.74 | ALOX5 (0.73) | NPC1KDM4EALDH1A1CASP3SENP7 | |
| SCHEMBL24552409 | 0.73 | AHR (0.55) | NPC1KDM4EALDH1A1CASP3SENP7 | |
| SCHEMBL31690261 | 0.72 | AHR (0.66) | NPC1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8964805 | 0.72 | KDM4E (0.52) | NPC1KDM4EALDH1A1CASP3SENP7 | |
| SCHEMBL8965506 | 0.72 | KDM4E (0.56) | NPC1KDM4EALDH1A1CASP3SENP7 | |
| SCHEMBL12203168 | 0.71 | KMT2A (0.58) | NPC1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5832494 | 0.71 | NPC1 (0.67) | NPC1KDM4EALDH1A1CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |