Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9076373 | 0.88 | ALDH1A1 (0.38) | P2RX3ALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8966362 | 0.87 | ALDH1A1 (0.36) | P2RX3ALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8965780 | 0.80 | ALDH1A1 (0.37) | P2RX3ALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8965791 | 0.80 | ALDH1A1 (0.37) | P2RX3ALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9075502 | 0.78 | ALDH1A1 (0.36) | P2RX3ALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9075507 | 0.78 | ALDH1A1 (0.36) | P2RX3ALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8965818 | 0.74 | PTGDR2 (0.43) | P2RX3ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL9076607 | 0.71 | ALDH1A1 (0.40) | P2RX3ALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9076604 | 0.71 | ALDH1A1 (0.40) | P2RX3ALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8966128 | 0.70 | GRM4 (0.41) | P2RX3ALDH1A1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509857-B1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1996-02-28 | — | — | EP | disclosed |
| EP-0509857-A1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1992-10-21 | — | — | EP | disclosed |